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Hundreds of current medical practices may be ineffective

Medical reversal” is a term that defines instances

Medical reversals occur when new clinical research shows that a certain medical practice does not, in fact, work or it does more harm than good.



These new studies are superior to their predecessors because of things like better controls, better study design, or larger sample size.

Medical reversals often concern medications but they can also affect surgical procedures.

For instance, more than a decade ago, researchers and healthcare professionals realized that stenting procedures did not work for renal artery stenosis and that routine stenting should not be used to treat stable coronary disease.

Now, a new meta-analysis of 3,000 studies identifies almost 400 cases of medical reversals. The review appears in the journal eLife.

Diana Herrera-Perez, a research assistant at the Knight Cancer Institute at Oregon Health & Science University (OHSU), in Portland, is the lead author of the new analysis.

Analysis finds 396 medical reversals

Referring to well-known endeavors to assess the validity of clinical practices, such as the Cochrane reviews, Herrera-Perez says, “We wanted to build on these and other efforts to provide a larger and more comprehensive list for clinicians and researchers to guide practice as they care for patients more effectively and economically.”

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